One step closer to in-vivo detection of low-grade gliomas

A pilot test confirms that spectral imaging can be a way towards intraoperative and label-free detection of intrinsic brain tumors.

Surgical microscope fitted with a hyperspectral camera in an operating room

Low-grade gliomas – a group of slow-growing brain tumors – are extremely difficult to detect. Their exact demarcations are hard to retrieve, even using surgical microscopes.

A way to detect these tumors in-vivo would therefore be a breakthrough for surgeons. In that respect, imec’s compact, high-accuracy hyperspectral cameras hold a lot of promise. As was demonstrated by intraoperative pilot tests at the University Hospital of Leuven.

An imec SNAPSCAN VNIR was mounted on a surgical microscope to generate clinical data. That data could then be fed into a deep-learning neural network. Resulting in the knowledge to enable surgeons to discriminate between healthy and anomalous tissue.

The next step is to move to video-rate hyperspectral imaging for real-time tumor classification.

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