New privacy-preserving AI can have a profound impact on the future of medicine

Data sharing is needed to advance medicine. But for practical, business, IP or legal reasons, sharing the data (such as with federated data approaches) or the models (such as with federated learning) is impossible or highly controversial. Fortunately, imec has developed a solution that protects patients’ privacy and businesses’ commercial interests

Stethoscope on medical charts beside a laptop, suggesting digital healthcare data analysis.

Pooling medical data could save countless lives. Artificial intelligence (AI) has the potential to transform our understanding of biology, optimize treatment decisions, and outperform humans in diagnosing illnesses like cancer. However, in order to work, AI algorithms need to be trained on large datasets.

Unfortunately, valuable health data is often dispersed over multiple data silos, each controlled by a different entity.

Examples may include GP surgeries, hospitals, labs, health insurers, pharma companies, and even the smart health gadgets many of us wear.

While these entities can apply their own AI models to their generated data, their models could benefit significantly from the data held in other silos. 

However, for practical, business, IP or legal reasons, sharing the data (such as with federated data approaches) or the models (such as with federated learning) is impossible or highly controversial.

The NHS recently proved this point when it tried to create the world's most valuable health dataset.

The plan was to centralize the GP records of more than 55 million patients. Though officials declared the NHS would pseudonymize the data, it remains possible to identify patients. Once the privacy ramifications became clear, public outrage forced the NHS to pause its plans.

This is not the first initiative to collect healthcare data on a massive scale, and we suspect it will not be the last.

One approach to preserve user privacy is called federated machine learning. Companies and researchers, however, often reject this approach because it relies on sharing valuable AI models. 

Apple's virtual assistant Siri is the most famous example of how federated machine learning works. First, each user trains their version of Siri on their device. Then, apple collects users' models and uses this information to improve the master model. This approach works for Apple because only one model is involved, but it becomes complicated when multiple models from multiple parties would be involved, since they would need to share their intellectual property. 

This issue has limited medical progress.

Imec is pioneering a new approach called ‘privacy-preserving amalgamated machine learning’ (PAML). PAML allows each participating entity to build their own model using only locally available data whilst indirectly incorporating information from other data silos in a way that does not compromise privacy or harm commercial interests. 

We consider PAML to be a significant technical breakthrough and hope it will soon be widely adopted by the medical community to ethically and sustainably advance science.

 

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Authors

Portrait of Roel Wuyts, a bearded man wearing glasses and a dark sweater against a blurred background.

Roel Wuyts

Team Lead ExaScience Life Lab
Author

Roel Wuyts is principal scientist at imec and part-time professor at imec- DistriNet – KU Leuven. His main research interest is in the runtime management layer of future high-performance computing hardware. Before joining imec, he was Associate Professor at the ULB (Université Libre de Bruxelles). He obtained his PhD in computer science from the VUB (Vrije Universiteit Brussel). Roel Wuyts has served as member in various conference program committees such as ECOOP, OOPSLA, SC, Net.ObjectDays, or ESUG, organized workshops such as the DATE'08 Workshop on Software Engineering for Embedded Systems, and reviewed papers for TOPLAS or TOSEM.

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